MC Jaco (Jacob Hughes) and The King (Robert King) wrote verses that were programmed into the devices, allowing their lines to be spoken.
Seven artists in total are featured in the music video for 'My World' which was released on YouTube at a red carpet event.
Peer worker with Community Disability Alliance Hunter (CDAH) Catherine Mahony said the release "could be a world first".
"It's certainly a first for Speak Up Hunter," Ms Mahony said
"We aren't aware of any other local music videos featuring people with intellectual disability."
The idea for a music video was developed by members of Speak Up Hunter, a peer support group for people with intellectual disability.
"It focuses on people with intellectual disability organising and participating in a range of activities," Ms Mahony said