First Successful Gene Therapy for Hemophilia A

One of these days I'm going to do a post on the holocaust that killed 95% of children with hemophilia by refusing to test blood for HIV. For now, this is a real first step to eliminating that dependence on human blood products....
https://goo.gl/85VDyc

A single infusion of a gene therapy for hemophilia A led to normalization of factor VIII levels that persisted for a year, British investigators reported here.

Six of seven patients treated with the highest dose of the engineered therapy had factor VIII levels >50 IU/dL, and the seventh patient had therapeutic levels of factor VIII at 1 year. The high-dose cohort averaged 16 bleeding episodes a year before treatment and one episode afterward.



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